H 89 2HCl

Catalog No.: A11935
PKA inhibitor
H 89 dihydrochloride is a cell-permeable, selective, reversible, ATP-competitive and potent inhibitor of protein kinase.
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Product Name Price Stock Qty
H 89 dihydrochloride 10mg
$50.00
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H 89 dihydrochloride 25mg
$100.00
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H 89 dihydrochloride 50mg
$160.00
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H 89 dihydrochloride 100mg
$280.00
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Adooq Products cited in reputable paper
Adooq's H 89 2HCl has been cited by 3 publications
  • Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418
  • Guo Q, .et al. , Biomed Pharmacother, 2020, Mar;123:109812 PMID: 31945696
  • Y Kaibori, .et al. , the FASEB Journal, 2019, Jan 22:fj201801519RR PMID: 30668924
  • Biological Activity
    Discription H 89 dihydrochloride is a cell-permeable, selective, reversible, ATP-competitive and potent inhibitor of protein kinase.
    Product Information
    Catalog Num A11935
    Formula C20H20BrN3O2S.2HCl
    Molecular Weight 519.3
    CAS Number 127243-85-0, 130964-39-5
    SMILES C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCNC/C=C/C3=CC=C(C=C3)Br.Cl.Cl
    Synonyms H89 2HCl
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 96 mg/mL (184.86 mM)
    Water 6 mg/mL (11.55 mM)
    Ethanol Insoluble
    In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.26 mL 96.28 mL 192.57 mL
    0.5 mM 3.85 mL 19.26 mL 38.51 mL
    1 mM 1.93 mL 9.63 mL 19.26 mL
    5 mM 0.39 mL 1.93 mL 3.85 mL
    Useful Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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