Harmol hydrochloride

Catalog No.: A31747
Monoamine Oxidase Inhibitor
Harmol hydrochloride is a potent monoamine oxidase inhibitor that functions as a transcription factor EB (TFEB) activator. It demonstrates significant biological activities, including the induction of cell mitosis, autophagy, and apoptosis. Additionally, Harmol hydrochloride promotes the degradation of α-synuclein by modulating the autophagy-lysosomal pathway, making it relevant in studies of neurodegenerative diseases. Its diverse pharmacological effects also extend to anti-tumor, anti-depressant, and anti-aging activities, and it has shown promise in alleviating motor impairments in models of Parkinson's disease.
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Size Price Stock Qty
10mg
$595.00
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHarmol hydrochloride is a potent monoamine oxidase inhibitor that functions as a transcription factor EB (TFEB) activator. It demonstrates significant biological activities, including the induction of cell mitosis, autophagy, and apoptosis. Additionally, Harmol hydrochloride promotes the degradation of α-synuclein by modulating the autophagy-lysosomal pathway, making it relevant in studies of neurodegenerative diseases. Its diverse pharmacological effects also extend to anti-tumor, anti-depressant, and anti-aging activities, and it has shown promise in alleviating motor impairments in models of Parkinson's disease.
Product Information
Catalog NumA31747
FormulaC12H11ClN2O
Molecular Weight234.68
CAS Number40580-83-4
SMILESOC1=CC2=C(C=C1)C3=C(C(C)=NC=C3)N2.[H]Cl
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