Hcyb1 is a highly selective inhibitor of phosphodiesterase 2 (PDE2), demonstrating an IC50 of 0.57 μM against PDE2A and over 250-fold selectivity towards other members of the phosphodiesterase family. This compound is characterized by its neuroprotective and antidepressant-like effects, which are likely mediated through the cAMP/cGMP-CREB-BDNF signaling pathway. Hcyb1 is a valuable tool for research applications focusing on neurobiology and mood disorders.
Hcyb1 is a highly selective inhibitor of phosphodiesterase 2 (PDE2), demonstrating an IC50 of 0.57 μM against PDE2A and over 250-fold selectivity towards other members of the phosphodiesterase family. This compound is characterized by its neuroprotective and antidepressant-like effects, which are likely mediated through the cAMP/cGMP-CREB-BDNF signaling pathway. Hcyb1 is a valuable tool for research applications focusing on neurobiology and mood disorders.
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