Helianorphin-19 is a potent and selective κ-opioid receptor (KOR) activator, exhibiting a Ki of 21 nM and an EC50 of 45 nM. It demonstrates significant KOR-specific peripheral analgesic activity in mouse models of chronic visceral pain. This compound is valuable for investigating the role of KOR in pain modulation and may provide insights into therapeutic approaches for pain management.
Helianorphin-19 is a potent and selective κ-opioid receptor (KOR) activator, exhibiting a Ki of 21 nM and an EC50 of 45 nM. It demonstrates significant KOR-specific peripheral analgesic activity in mouse models of chronic visceral pain. This compound is valuable for investigating the role of KOR in pain modulation and may provide insights into therapeutic approaches for pain management.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
