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Hemopressin(human, mouse) TFA

Catalog No.: A59301
Cannabinoid Receptor Antagonist
Hemopressin (human, mouse) TFA targets the cannabinoid CB1 receptor as a selective inverse agonist. This nonapeptide, derived from the α1-chain of hemoglobin and originally isolated from rat brain homogenates, demonstrates oral bioavailability. Hemopressin TFA has been shown to exert antinociceptive effects in models of inflammatory pain, making it valuable for research in pain management and cannabinoid signaling pathways.
Hemopressin(human, mouse) TFA 1431329-48-4 Cannabinoid Receptor Antagonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHemopressin (human, mouse) TFA targets the cannabinoid CB1 receptor as a selective inverse agonist. This nonapeptide, derived from the α1-chain of hemoglobin and originally isolated from rat brain homogenates, demonstrates oral bioavailability. Hemopressin TFA has been shown to exert antinociceptive effects in models of inflammatory pain, making it valuable for research in pain management and cannabinoid signaling pathways.
Product Information
Catalog NumA59301
FormulaC52H80F3N13O14
Molecular Weight1168.27
CAS Number1431329-48-4
SequencePro-Val-Asn-Phe-Lys-Leu-Leu-Ser-His
Sequence shorteningPVNFKLLSH
SMILESC(C(O)=O)(F)(F)F.[C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@@H](NC(=O)[C@@H]2CCCN2)[C@H](C)C)=O)CC(N)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CN=CN3)C(O)=O)=O)CO)=O)CC(C)C)=O)CC(C)C)=O)CCCCN)=O
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GPCR/G Protein > Cannabinoid Receptors