Henagliflozin is a selective sodium-glucose co-transporter 2 (SGLT2) inhibitor with an IC50 value of 2.38 nM for human SGLT2, exhibiting minimal activity against SGLT1 with an IC50 of 4324 nM. This compound is instrumental in diabetes research, facilitating studies on glucose homeostasis and potential therapeutic strategies for diabetic conditions. Its high selectivity and potency make it a valuable tool for investigating the physiological and pharmacological roles of SGLT2 in metabolic disorders.
Henagliflozin is a selective sodium-glucose co-transporter 2 (SGLT2) inhibitor with an IC50 value of 2.38 nM for human SGLT2, exhibiting minimal activity against SGLT1 with an IC50 of 4324 nM. This compound is instrumental in diabetes research, facilitating studies on glucose homeostasis and potential therapeutic strategies for diabetic conditions. Its high selectivity and potency make it a valuable tool for investigating the physiological and pharmacological roles of SGLT2 in metabolic disorders.
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