HG-9-91-01

Catalog No.: A21004

SIK inhibitor

HG-9-91-01

HG-9-91-01 Chemical Structure

CAS NO. 1456858-58-4

HG-9-91-01 is a potent and highly selective salt-inducible kinase (SIK) inhibitor with IC50s of 0.92 nM, 6.6 nM and 9.6 nM for SIK1, SIK2 and SIK3 respectively.

Availability: In stock

Package Price Qty
5 mg
$257.00
10 mg
$443.00
50 mg
$1,316.00
100 mg
$2,631.00
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Biological Activity

HG-9-91-01 is a potent and highly selective salt-inducible kinase (SIK) inhibitor with IC50s of 0.92 nM, 6.6 nM and 9.6 nM for SIK1, SIK2 and SIK3 respectively.
In vitro DMSO 91 mg/mL (160.3 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.62 mL 88.08 mL 176.16 mL
0.5 mM 3.52 mL 17.62 mL 35.23 mL
1 mM 1.76 mL 8.81 mL 17.62 mL
5 mM 0.35 mL 1.76 mL 3.52 mL

*The above data is based on the productmolecular weight 567.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21004
Actions Inhibitor
CAS No. 1456858-58-4
Formula C32H37N7O3
M. Wt 567.68
Purity >98%
SMILES CC1=CC=CC(C)=C1NC(N(C2=NC=NC(NC3=CC=C(N4CCN(C)CC4)C=C3)=C2)C5=CC=C(OC)C=C5OC)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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