Hibarimicin A is a selective Src tyrosine kinase inhibitor derived from Microbispora rosea subsp. hibaria. It effectively inhibits Src activity while sparing protein kinases A and C, making it a valuable tool for studying cellular signaling pathways involving Src. In addition to its role as a kinase inhibitor, Hibarimicin A exhibits moderate antibacterial activity against Gram-positive bacteria, with a minimum inhibitory concentration (MIC) ranging from 0.8 to 12.56 μg/mL, broadening its potential applications in microbiology and pharmacology research.
Hibarimicin A is a selective Src tyrosine kinase inhibitor derived from Microbispora rosea subsp. hibaria. It effectively inhibits Src activity while sparing protein kinases A and C, making it a valuable tool for studying cellular signaling pathways involving Src. In addition to its role as a kinase inhibitor, Hibarimicin A exhibits moderate antibacterial activity against Gram-positive bacteria, with a minimum inhibitory concentration (MIC) ranging from 0.8 to 12.56 μg/mL, broadening its potential applications in microbiology and pharmacology research.
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