HIF-1α-IN-2 is a potent inhibitor of HIF-1α, demonstrating significant anticancer activity with IC50 values of 28 nM and 15 nM in MDA-MB-231 and MiaPaCa-2 cell lines, respectively. This compound functions by inhibiting the transcription and translation of HIF-1α, effectively suppressing its expression. HIF-1α-IN-2 is applicable in research exploring hypoxia-induced tumor progression and therapeutic resistance in cancer studies.
HIF-1α-IN-2 is a potent inhibitor of HIF-1α, demonstrating significant anticancer activity with IC50 values of 28 nM and 15 nM in MDA-MB-231 and MiaPaCa-2 cell lines, respectively. This compound functions by inhibiting the transcription and translation of HIF-1α, effectively suppressing its expression. HIF-1α-IN-2 is applicable in research exploring hypoxia-induced tumor progression and therapeutic resistance in cancer studies.
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