HN37 is a potent activator of the KCNQ2 potassium channel, exhibiting an EC50 of 37 nM. This compound serves as a promising candidate in the development of antiepileptic therapies. Additionally, HN37 contains an alkyne group, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, enabling versatile applications in chemical biology and drug discovery.
HN37 is a potent activator of the KCNQ2 potassium channel, exhibiting an EC50 of 37 nM. This compound serves as a promising candidate in the development of antiepileptic therapies. Additionally, HN37 contains an alkyne group, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, enabling versatile applications in chemical biology and drug discovery.
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