HS-10296 hydrochloride

Catalog No.: A21661

EGFR/T790M inhibitor

HS-10296 hydrochloride

HS-10296 hydrochloride Chemical Structure

CAS NO. 2134096-03-8

HS-10296 hydrochloride is an orally available and third-Generation inhibitor of epidermal growth factor receptor (EGFR)-activating mutations and T790M-resistant mutation with limited activity against wild-type EGFR.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $495.00

Special Price $396.00

10 mg

Regular Price: $853.00

Special Price $682.40

50 mg

Regular Price: $2,530.00

Special Price $2,024.00

100 mg

Regular Price: $5,060.00

Special Price $4,048.00

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Biological Activity

HS-10296 hydrochloride is an orally available and third-Generation inhibitor of epidermal growth factor receptor (EGFR)-activating mutations and T790M-resistant mutation with limited activity against wild-type EGFR.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.79 mL 88.95 mL 177.9 mL
0.5 mM 3.56 mL 17.79 mL 35.58 mL
1 mM 1.78 mL 8.9 mL 17.79 mL
5 mM 0.36 mL 1.78 mL 3.56 mL

*The above data is based on the productmolecular weight 562.11. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21661
Actions Inhibitor
CAS No. 2134096-03-8
Formula C30H36ClN7O2
M. Wt 562.11
Purity >98%
Synonyms HS10296, HS 10296
SMILES COC(C=C(N(C)CCN(C)C)C(NC(C=C)=O)=C1)=C1NC2=NC(C3=CN(C4CC4)C5=C3C=CC=C5)=CC=N2.[H]Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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