Fig. 1 · Structure
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Human PD-L1 inhibitor III
PD-1/PD-L1 Inhibitor
Human PD-L1 Inhibitor III is a selective inhibitor targeting the PD-1/PD-L1 pathway, which plays a critical role in immune evasion by tumors. By blocking the interaction between programmed cell death protein 1 (PD-1) and its ligand PD-L1, this compound enhances T-cell activity, promoting anti-tumor immune responses. It is valuable for researchers investigating cancer immunotherapy and assessing therapeutic strategies aimed at modulating immune checkpoint pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2135542-84-4 |
| Applications | PD-1/PD-L1 Inhibitor |
| Formula | C97H155N29O29S1 |
| Molecular Weight | 2223.70 |
| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.