Human PD-L1 inhibitor V

Catalog No.: A35697
hPD-1/hPD-L1 Interaction Inhibitor
Human PD-L1 inhibitor V is a peptide that specifically targets the interaction between human PD-1 and PD-L1, exhibiting a binding affinity characterized by a Kd value of 3.32 μM. This inhibitor is valuable for research applications focused on immune checkpoint modulation and cancer immunotherapy, as it effectively disrupts the PD-1/PD-L1 signaling pathway, which is critical in the regulation of immune responses.
Grouped product items
Size Price Stock Qty
5mg
$155.00
In stock
10mg
$245.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHuman PD-L1 inhibitor V is a peptide that specifically targets the interaction between human PD-1 and PD-L1, exhibiting a binding affinity characterized by a Kd value of 3.32 μM. This inhibitor is valuable for research applications focused on immune checkpoint modulation and cancer immunotherapy, as it effectively disrupts the PD-1/PD-L1 signaling pathway, which is critical in the regulation of immune responses.
Product Information
Catalog NumA35697
FormulaC65H104N20O18S
Molecular Weight1485.71
CAS Number2815311-61-4
SequenceLeu-Asp-Tyr-Val-Asn-Arg-Arg-Lys-Met-Tyr-Gln
Sequence shorteningLDYVNRRKMYQ
SMILES[C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@H](CC(C)C)N)=O)CC(O)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)CCSC)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(N)=O)=O)[C@H](C)C)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2