Fig. 1 · Structure
Documents & Downloads
Human PD-L1 inhibitor V
hPD-1/hPD-L1 Interaction Inhibitor
Human PD-L1 inhibitor V is a peptide that specifically targets the interaction between human PD-1 and PD-L1, exhibiting a binding affinity characterized by a Kd value of 3.32 μM. This inhibitor is valuable for research applications focused on immune checkpoint modulation and cancer immunotherapy, as it effectively disrupts the PD-1/PD-L1 signaling pathway, which is critical in the regulation of immune responses.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2815311-61-4 |
| Applications | hPD-1/hPD-L1 Interaction Inhibitor |
| Formula | C65H104N20O18S |
| Molecular Weight | 1485.71 |
| SMILES | [C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@H](CC(C)C)N)=O)CC(O)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)CCSC)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(N)=O)=O)[C@H](C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.