(-)-Huperzine A

Catalog No.: A10006

GluR inhibitor

(-)-Huperzine A

(-)-Huperzine A Chemical Structure

CAS NO. 102518-79-6

(-)-Huperzine A is a naturally occurring sesquiterpene alkaloid compound found in the firmoss Huperzia serrata.

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Takuya Ohba, .et al. Protective effects of Huperzia serrata and its components against oxidative damage and cognitive dysfunction, PharmaNutrition, 2020, 13:100203

Biological Activity

(-)-Huperzine A is a naturally occurring sesquiterpene alkaloid compound found in the firmoss Huperzia serrata.
AChE (G4 form)
7 nM(Ki)
In vitro (25°C) DMSO 0.66 mg/mL (2.72 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 41.27 mL 206.36 mL 412.71 mL
0.5 mM 8.25 mL 41.27 mL 82.54 mL
1 mM 4.13 mL 20.64 mL 41.27 mL
5 mM 0.83 mL 4.13 mL 8.25 mL

*The above data is based on the productmolecular weight 242.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10006
Actions Inhibitor
M. Wt 242.3
Formula C15H18N2O
Solubility DMSO>49mg/mL Water>49mg/mL Ethanol<1mg/mL
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 102518-79-6
SMILES C/C=C\1/[[email protected]@H]2CC3=C([[email protected]]1(CC(=C2)C)N)C=CC(=O)N3

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