Hydroxy-PEG4-(CH2)2-Boc

Catalog No.: A42717
ADC Linker
Hydroxy-PEG4-(CH2)2-Boc is an uncleavable linker designed for use in the synthesis of antibody-drug conjugates (ADCs), facilitating stable conjugation between antibodies and therapeutic agents. Its structure supports efficient delivery of cytotoxic drugs specifically to target cells, enhancing therapeutic efficacy while minimizing off-target effects. Additionally, Hydroxy-PEG4-(CH2)2-Boc serves as a PROTAC linker, making it suitable for the development of proteolysis-targeting chimeras that promote the targeted degradation of specific proteins in various research applications.
Grouped product items
Size Price Stock Qty
200mg
$25.00
In stock
1g
$30.00
In stock
5g
$55.00
In stock
10g
$110.00
In stock
25g
$215.00
In stock
100g
$625.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHydroxy-PEG4-(CH2)2-Boc is an uncleavable linker designed for use in the synthesis of antibody-drug conjugates (ADCs), facilitating stable conjugation between antibodies and therapeutic agents. Its structure supports efficient delivery of cytotoxic drugs specifically to target cells, enhancing therapeutic efficacy while minimizing off-target effects. Additionally, Hydroxy-PEG4-(CH2)2-Boc serves as a PROTAC linker, making it suitable for the development of proteolysis-targeting chimeras that promote the targeted degradation of specific proteins in various research applications.
Product Information
Catalog NumA42717
FormulaC15H30O7
Molecular Weight322.39
CAS Number518044-32-1
SMILESO=C(OC(C)(C)C)CCOCCOCCOCCOCCO
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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