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Biological Activity
Hyperforin is a phytochemical produced by some of the members of the plant genus Hypericum, notably Hypericum perforatum (St John's wort). It inhibits the activity of several CYP450 enzymes, with CYP2D6 being the most sensitive with an IC50 of about 10 ug/ml. Hyperforin is also a ligand for the steroid X receptor (SXR).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.63 mL | 93.14 mL | 186.29 mL |
| 0.5 mM | 3.73 mL | 18.63 mL | 37.26 mL |
| 1 mM | 1.86 mL | 9.31 mL | 18.63 mL |
| 5 mM | 0.37 mL | 1.86 mL | 3.73 mL |
*The above data is based on the productmolecular weight 536.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12068 |
|---|---|
| CAS No. | 11079-53-1 |
| Formula | C35H52O4 |
| M. Wt | 536.8 |
| Purity | >98% |
| SMILES | CC(C)C(=O)C12C(=O)C(=C([[email protected]@](C1=O)(C[[email protected]@H]([[email protected]@]2(C)CCC=C(C)C)CC=C(C)C)CC=C(C)C)O)CC=C(C)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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