Hypophyllanthin is a significant lignan derived from Phyllanthus species that acts as a potent inhibitor of P-glycoprotein (P-gp). This compound exhibits strong anti-inflammatory properties and selectively inhibits P-gp activity without affecting multidrug resistance protein 2 (MRP2) activity. Its unique mechanism makes it a valuable tool for research in drug resistance and inflammation-related studies.
Hypophyllanthin is a significant lignan derived from Phyllanthus species that acts as a potent inhibitor of P-glycoprotein (P-gp). This compound exhibits strong anti-inflammatory properties and selectively inhibits P-gp activity without affecting multidrug resistance protein 2 (MRP2) activity. Its unique mechanism makes it a valuable tool for research in drug resistance and inflammation-related studies.
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