Biological Activity
IAXO-102 is a TLR4 antagonist which negatively regulates TLR4 signalling. It inhibits MAPK and p65 NF-κB phosphorylation and expression of TLR4 dependent proinflammatory protein.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 17.07 mL | 85.33 mL | 170.67 mL |
0.5 mM | 3.41 mL | 17.07 mL | 34.13 mL |
1 mM | 1.71 mL | 8.53 mL | 17.07 mL |
5 mM | 0.34 mL | 1.71 mL | 3.41 mL |
*The above data is based on the productmolecular weight 585.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A18543 |
---|---|
Actions | Antagonist |
M. Wt | 585.94 |
Formula | C35H71NO5 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1115270-63-7 |
Synonyms | IAXO102, IAXO 102 |
SMILES | CCCCCCCCCCCCCCO[[email protected]@H]1[[email protected]]([[email protected]@H]([[email protected]@H](CN)O[[email protected]@H]1OC)O)OCCCCCCCCCCCCCC |
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