IAXO-102

Catalog No.: A18543

TLR4 antagonist

IAXO-102

IAXO-102 Chemical Structure

CAS NO. 1115270-63-7

IAXO-102 is a TLR4 antagonist which negatively regulates TLR4 signalling. It inhibits MAPK and p65 NF-κB phosphorylation and expression of TLR4 dependent proinflammatory protein.

Availability: In stock

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5 mg

Regular Price: $300.00

Special Price $240.00

10 mg

Regular Price: $500.00

Special Price $400.00

50 mg

Regular Price: $1,500.00

Special Price $1,200.00

100 mg

Regular Price: $2,500.00

Special Price $2,000.00

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Biological Activity

IAXO-102 is a TLR4 antagonist which negatively regulates TLR4 signalling. It inhibits MAPK and p65 NF-κB phosphorylation and expression of TLR4 dependent proinflammatory protein.
In vitro DMSO 13 mg/mL (22.18 mM)
Water Insoluble
Ethanol 85 mg/mL (145.06 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.07 mL 85.33 mL 170.67 mL
0.5 mM 3.41 mL 17.07 mL 34.13 mL
1 mM 1.71 mL 8.53 mL 17.07 mL
5 mM 0.34 mL 1.71 mL 3.41 mL

*The above data is based on the productmolecular weight 585.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18543
Actions Antagonist
CAS No. 1115270-63-7
Formula C35H71NO5
M. Wt 585.94
Purity >98%
Synonyms IAXO102, IAXO 102
SMILES CCCCCCCCCCCCCCO[[email protected]@H]1[[email protected]]([[email protected]@H]([[email protected]@H](CN)O[[email protected]@H]1OC)O)OCCCCCCCCCCCCCC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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