Biological Activity
Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm. It exerts its antiarrhythmic effect by induction of slow inward sodium current, which prolongs action potential and refractory period (physiology) of myocardial cells.
In vitro | DMSO | 88 mg/mL (99.4 mM) | |
Water | 88 mg/mL (99.4 mM) | ||
Ethanol | 88 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 11.3 mL | 56.48 mL | 112.97 mL |
0.5 mM | 2.26 mL | 11.3 mL | 22.59 mL |
1 mM | 1.13 mL | 5.65 mL | 11.3 mL |
5 mM | 0.23 mL | 1.13 mL | 2.26 mL |
*The above data is based on the productmolecular weight 885.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A11750 |
---|---|
CAS No. | 122647-32-9 |
Formula | (C20H36N2O3S)2.C4H4O |
M. Wt | 885.2 |
Solubility | DMSO |
Purity | >98% |
SMILES | CCCCCCCN(CC)CCCC(C1=CC=C(C=C1)NS(=O)(=O)C)O.CCCCCCCN(CC)CCCC(C1=CC=C(C=C1)NS(=O)(=O)C)O.C(=C/C(=O)O)\C(=O)O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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