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$0.00 - Moon Jain, .et al. Involvement of angiotensin II and beta-adrenergic receptors in the regulation of autophagy in human endothelial EA.hy926 cell line, Tropical Journal of Pharmaceutical Research, 2020, Vol. 19 No. 4
Biological Activity
ICI-118551 is a selective beta2 adrenergic receptor (adrenoreceptor) antagonist.
Targets
| β2-adrenergic receptor | β1-adrenergic receptor | β3-adrenoceptor | ||
| 0.7nM(Ki) | 49.5nM(Ki) | 611nM(Ki) |
| In vitro | DMSO | 59 mg/mL (187.98 mM) | |
| Water | 20 mg/mL (63.71 mM) | ||
| Ethanol | 59 mg/mL (187.98 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.86 mL | 159.31 mL | 318.61 mL |
| 0.5 mM | 6.37 mL | 31.86 mL | 63.72 mL |
| 1 mM | 3.19 mL | 15.93 mL | 31.86 mL |
| 5 mM | 0.64 mL | 3.19 mL | 6.37 mL |
*The above data is based on the productmolecular weight 313.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15878 |
|---|---|
| Actions | Antagonist |
| CAS No. | 1217094-53-5 |
| Formula | C17H27NO2.HCl |
| M. Wt | 313.86 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | ICI118551, ICI 118551 |
| SMILES | CC1=C(CCC2)C2=C(OC[[email protected]](O)[[email protected]@H](C)NC(C)C)C=C1.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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