ICMT-IN-1 is a selective inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT) with an IC50 of 0.0013 μM. This compound has been shown to effectively induce the accumulation of ICMT in the cytoplasm of HCT-116 cells. Additionally, ICMT-IN-1 exhibits significant antiproliferative activity against various cancer cell lines that express K-Ras and N-Ras, making it a valuable tool for research in cancer biology and therapeutic development.
ICMT-IN-1 is a selective inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT) with an IC50 of 0.0013 μM. This compound has been shown to effectively induce the accumulation of ICMT in the cytoplasm of HCT-116 cells. Additionally, ICMT-IN-1 exhibits significant antiproliferative activity against various cancer cell lines that express K-Ras and N-Ras, making it a valuable tool for research in cancer biology and therapeutic development.
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