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ICMT-IN-26

Catalog No.: A60930
ICMT Inhibitor
ICMT-IN-26 is a selective inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), with an IC50 value of 0.36 μM. This compound is utilized in biochemical research to investigate the role of ICMT in protein modification and signal transduction pathways. Its inhibition profile makes it a valuable tool for studying diseases associated with dysregulated protein methylation.
ICMT-IN-26 1313602-84-4 ICMT Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionICMT-IN-26 is a selective inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), with an IC50 value of 0.36 μM. This compound is utilized in biochemical research to investigate the role of ICMT in protein modification and signal transduction pathways. Its inhibition profile makes it a valuable tool for studying diseases associated with dysregulated protein methylation.
Product Information
Catalog NumA60930
FormulaC21H26ClNO
Molecular Weight343.89
CAS Number1313602-84-4
SMILESCC1(C)CC(CCNC2=CC=C(Cl)C=C2)(C3=CC=CC=C3)CCO1
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GPCR/G Protein > ICMT