ICMT-IN-52

Catalog No.: A60910
ICMT Inhibitor
ICMT-IN-52 is a specific inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting an IC50 value of 0.052 μM. This compound plays a crucial role in research on post-translational modifications and protein maturation related to oncogenesis and cellular signaling. Its ability to effectively inhibit ICMT makes it a valuable tool for studying the biological implications of ICMT activity in various disease models.
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5mg
10mg
50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionICMT-IN-52 is a specific inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting an IC50 value of 0.052 μM. This compound plays a crucial role in research on post-translational modifications and protein maturation related to oncogenesis and cellular signaling. Its ability to effectively inhibit ICMT makes it a valuable tool for studying the biological implications of ICMT activity in various disease models.
Product Information
Catalog NumA60910
FormulaC21H26FNO
Molecular Weight327.44
CAS Number1313602-90-2
SMILESFC1=CC(NCCC2(C3=CC=CC=C3)CC(C)(C)OCC2)=CC=C1
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