ICMT-IN-54 is an adamantyl analogue that functions as an inhibitor of Isoprenylcysteine Carboxyl Methyltransferase (ICMT), exhibiting an IC50 value of 12.4 μM. This compound effectively inhibits the methylation of BFC (N-biotinyl-(6-aminohexanoic)-S-farnesyl-L-cysteine) in Saccharomyces cerevisiae expressing ICMT, thereby demonstrating its potential to interfere with ICMT-mediated methylation processes. ICMT-IN-54 is a valuable tool for research into the roles of ICMT in cellular signaling and protein modification.
ICMT-IN-54 is an adamantyl analogue that functions as an inhibitor of Isoprenylcysteine Carboxyl Methyltransferase (ICMT), exhibiting an IC50 value of 12.4 μM. This compound effectively inhibits the methylation of BFC (N-biotinyl-(6-aminohexanoic)-S-farnesyl-L-cysteine) in Saccharomyces cerevisiae expressing ICMT, thereby demonstrating its potential to interfere with ICMT-mediated methylation processes. ICMT-IN-54 is a valuable tool for research into the roles of ICMT in cellular signaling and protein modification.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
