ICMT-IN-7 is a potent inhibitor of isoprenylcysteine methyltransferase (ICMT), with an IC50 of 0.015 μM. This compound effectively induces the accumulation of ICMT in the cytoplasm of HCT-116 cells and demonstrates significant inhibitory effects on the proliferation of various cancer cell lines that express K-Ras and N-Ras. ICMT-IN-7 is valuable for research applications targeting ICMT-related pathways in cancer biology.
ICMT-IN-7 is a potent inhibitor of isoprenylcysteine methyltransferase (ICMT), with an IC50 of 0.015 μM. This compound effectively induces the accumulation of ICMT in the cytoplasm of HCT-116 cells and demonstrates significant inhibitory effects on the proliferation of various cancer cell lines that express K-Ras and N-Ras. ICMT-IN-7 is valuable for research applications targeting ICMT-related pathways in cancer biology.
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