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ICMT-IN-8

Catalog No.: A60927
ICMT Inhibitor
ICMT-IN-8 is a potent inhibitor of Isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting an IC50 value of 0.652 μM. This compound is primarily utilized in research applications focusing on protein prenylation and related signaling pathways. Investigating ICMT's role can provide insights into its potential implications in cancer and other diseases linked to dysregulated protein modification.
ICMT-IN-8 1313602-76-4 ICMT Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionICMT-IN-8 is a potent inhibitor of Isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting an IC50 value of 0.652 μM. This compound is primarily utilized in research applications focusing on protein prenylation and related signaling pathways. Investigating ICMT's role can provide insights into its potential implications in cancer and other diseases linked to dysregulated protein modification.
Product Information
Catalog NumA60927
FormulaC23H31NO3
Molecular Weight369.50
CAS Number1313602-76-4
SMILESCOC1=CC=C(C=C1OC)NCCC2(C3=CC=CC=C3)CC(C)(C)OCC2
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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GPCR/G Protein > ICMT