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Biological Activity
IDO-IN-5 (NLG-1489) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1489, has an IC50 of 1-10 μM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.61 mL | 158.04 mL | 316.09 mL |
| 0.5 mM | 6.32 mL | 31.61 mL | 63.22 mL |
| 1 mM | 3.16 mL | 15.8 mL | 31.61 mL |
| 5 mM | 0.63 mL | 3.16 mL | 6.32 mL |
*The above data is based on the productmolecular weight 316.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21074 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1402837-79-9 |
| Formula | C18H21FN2O2 |
| M. Wt | 316.37 |
| Purity | >98% |
| Synonyms | NLG-1489, NLG1489, NLG 1489 |
| SMILES | O[C@H](CC1)CC[C@]1([H])[C@H](O)C[C@H]2N3C(C4=C2C(F)=CC=C4)=CN=C3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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