IDO/TDO-IN-1

Catalog No.: A18566

IDO/TDO dual inhibitor

IDO/TDO-IN-1

IDO/TDO-IN-1 Chemical Structure

CAS NO. 2033173-01-0

IDO/TDO-IN-1 is a highly potent and orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor with IC50s of 9.7 and 47 nM, respectively .

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
50 mg
$2,000.00
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Biological Activity

IDO/TDO-IN-1 is a highly potent and orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor with IC50s of 9.7 and 47 nM, respectively .
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.18 mL 120.92 mL 241.84 mL
0.5 mM 4.84 mL 24.18 mL 48.37 mL
1 mM 2.42 mL 12.09 mL 24.18 mL
5 mM 0.48 mL 2.42 mL 4.84 mL

*The above data is based on the productmolecular weight 413.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18566
Actions Inhibitor
CAS No. 2033173-01-0
Formula C25H24FN5
M. Wt 413.49
Purity >98%
SMILES CN1N=CC(C2=CC=C(N3CCC([[email protected]@H](C4=C5C=CC=C4F)N6C5=CN=C6)CC3)C=C2)=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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