IDO1/2-IN-1 hydrochloride is a potent dual inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1) and indoleamine 2,3-dioxygenase 2 (IDO2), with IC50 values of 28 nM and 144 nM, respectively. This compound demonstrates significant antitumor activity, making it a valuable tool for cancer research. Its oral bioavailability facilitates its use in various biological studies aimed at understanding immune modulation and tumor microenvironment interactions.
IDO1/2-IN-1 hydrochloride is a potent dual inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1) and indoleamine 2,3-dioxygenase 2 (IDO2), with IC50 values of 28 nM and 144 nM, respectively. This compound demonstrates significant antitumor activity, making it a valuable tool for cancer research. Its oral bioavailability facilitates its use in various biological studies aimed at understanding immune modulation and tumor microenvironment interactions.
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