IDO1/2-IN-1 is a novel dual inhibitor targeting indoleamine 2,3-dioxygenase 1 (IDO1) and IDO2, with IC50 values of 28 nM and 144 nM, respectively. This compound demonstrates significant antitumor activity, making it a valuable tool for cancer research. The orally active nature of IDO1/2-IN-1 enhances its potential for in vivo studies, facilitating the exploration of immunomodulatory effects and therapeutic applications in oncology.
IDO1/2-IN-1 is a novel dual inhibitor targeting indoleamine 2,3-dioxygenase 1 (IDO1) and IDO2, with IC50 values of 28 nM and 144 nM, respectively. This compound demonstrates significant antitumor activity, making it a valuable tool for cancer research. The orally active nature of IDO1/2-IN-1 enhances its potential for in vivo studies, facilitating the exploration of immunomodulatory effects and therapeutic applications in oncology.
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