IDO1-IN-11

Catalog No.: A75736
IDO Inhibitor
IDO1-IN-11 is a potent inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1) with an IC50 value of 0.6 nM. This compound exhibits significant activity in modulating immune responses by inhibiting tryptophan catabolism, thereby enhancing T cell function. IDO1-IN-11 is valuable for research applications investigating cancer immunotherapy and immune regulation.
Grouped product items
Size Price Stock Qty
5mg
$795.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionIDO1-IN-11 is a potent inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1) with an IC50 value of 0.6 nM. This compound exhibits significant activity in modulating immune responses by inhibiting tryptophan catabolism, thereby enhancing T cell function. IDO1-IN-11 is valuable for research applications investigating cancer immunotherapy and immune regulation.
Product Information
Catalog NumA75736
FormulaC22H17ClFN3O3
Molecular Weight425.84
CAS Number2306411-34-5
SMILESO=C(C1=CC(Cl)=CC=C1)NC2=CN=C(C3(COC3)C(NC4=CC=C(C=C4)F)=O)C=C2
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