IDO1-IN-17 is a selective inhibitor of the enzyme indoleamine 2,3-dioxygenase 1 (IDO1), exhibiting an IC50 of 0.44 μM in HeLa cells. By blocking IDO1, this compound modulates the kynurenine pathway and impairs tryptophan catabolism, leading to enhanced immune response. IDO1-IN-17 is a valuable tool for research into cancer immunotherapy and the exploration of immune metabolism.
IDO1-IN-17 is a selective inhibitor of the enzyme indoleamine 2,3-dioxygenase 1 (IDO1), exhibiting an IC50 of 0.44 μM in HeLa cells. By blocking IDO1, this compound modulates the kynurenine pathway and impairs tryptophan catabolism, leading to enhanced immune response. IDO1-IN-17 is a valuable tool for research into cancer immunotherapy and the exploration of immune metabolism.
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