IDO1-IN-22 is a potent inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with biochemical and cellular IC50 values of 67.4 nM and 17.6 nM, respectively, in human HeLa cells. This compound demonstrates significant antitumor activity in LLC xenograft models and possesses a favorable pharmacokinetic profile, making it a valuable tool for cancer research and therapeutic development targeting immune modulation pathways.
IDO1-IN-22 is a potent inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with biochemical and cellular IC50 values of 67.4 nM and 17.6 nM, respectively, in human HeLa cells. This compound demonstrates significant antitumor activity in LLC xenograft models and possesses a favorable pharmacokinetic profile, making it a valuable tool for cancer research and therapeutic development targeting immune modulation pathways.
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