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IDO1-IN-29

Catalog No.: A75747
Apo-IDO1 Inhibitor
IDO1-IN-29 is a selective inhibitor of apo-IDO1, exhibiting an IC50 of 0.29 μM. This compound effectively disrupts heme binding, making it a valuable tool for investigating the role of IDO1 in cancer biology. IDO1-IN-29 is particularly useful for researchers studying tumor immune evasion and exploring novel therapeutic strategies in oncology.
IDO1-IN-29 1219340-38-1 Apo-IDO1 Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionIDO1-IN-29 is a selective inhibitor of apo-IDO1, exhibiting an IC50 of 0.29 μM. This compound effectively disrupts heme binding, making it a valuable tool for investigating the role of IDO1 in cancer biology. IDO1-IN-29 is particularly useful for researchers studying tumor immune evasion and exploring novel therapeutic strategies in oncology.
Product Information
Catalog NumA75747
FormulaC26H27N3O3
Molecular Weight429.51
CAS Number1219340-38-1
SMILESO=C(NC(CC1=CC=CC=C1)C(N2C3=C(CC2)C=CC=C3)=O)NC4=C(OCC)C=CC=C4
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Metabolism > IDO