IDO1-IN-32

Catalog No.: A75765
IDO1 Inhibitor
IDO1-IN-32 is a highly effective inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), exhibiting an impressive IC50 of 10 pM. This compound demonstrates marked anti-proliferative effects in HeLa cells and has been shown to significantly inhibit tumor growth in CT26 and LCC models in vivo, primarily through the activation of anti-tumor immunity. IDO1-IN-32 is valuable for research exploring therapies in colon and breast cancer.
Grouped product items
Size Stock
5mg
10mg
50mg
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionIDO1-IN-32 is a highly effective inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), exhibiting an impressive IC50 of 10 pM. This compound demonstrates marked anti-proliferative effects in HeLa cells and has been shown to significantly inhibit tumor growth in CT26 and LCC models in vivo, primarily through the activation of anti-tumor immunity. IDO1-IN-32 is valuable for research exploring therapies in colon and breast cancer.
Product Information
Catalog NumA75765
FormulaC26H29Cl2FN4O3
Molecular Weight535.44
CAS Number2456309-77-4
SMILESO=C(C1=CC=CN1C2=CC(NC(NC3=CC=C(Cl)C=C3F)=O)=C(N(CC(C)C)CC(C)C)C(Cl)=C2)O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2