IDO1/TDO-IN-3 is a potent inhibitor targeting both indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO). It demonstrates significant inhibitory potency with IC50 values of 0.005 μM for IDO1 and 0.004 μM for TDO. This compound exhibits considerable anti-tumor activity in vivo while displaying no apparent toxicity, making it a valuable tool for studies in cancer immunotherapy and metabolism.
IDO1/TDO-IN-3 is a potent inhibitor targeting both indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO). It demonstrates significant inhibitory potency with IC50 values of 0.005 μM for IDO1 and 0.004 μM for TDO. This compound exhibits considerable anti-tumor activity in vivo while displaying no apparent toxicity, making it a valuable tool for studies in cancer immunotherapy and metabolism.
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