IDO1/TDO-IN-9 is a potent dual inhibitor targeting indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO), exhibiting IC50 values of less than 1 μM. This compound effectively inhibits the enzymatic activity of IDO1 and TDO, thereby blocking the degradation of tryptophan to kynurenine. By restoring immune activity within the tumor microenvironment, IDO1/TDO-IN-9 shows potential in suppressing tumor growth, making it a valuable tool for cancer research.
IDO1/TDO-IN-9 is a potent dual inhibitor targeting indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO), exhibiting IC50 values of less than 1 μM. This compound effectively inhibits the enzymatic activity of IDO1 and TDO, thereby blocking the degradation of tryptophan to kynurenine. By restoring immune activity within the tumor microenvironment, IDO1/TDO-IN-9 shows potential in suppressing tumor growth, making it a valuable tool for cancer research.
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