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IEM 1754 Dihydrobromide

AMPA Receptor Blocker

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Catalog No. A14010

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
IEM 1754 Dihydrobromide 10mg A14010-10
IEM 1754 Dihydrobromide 25mg A14010-25
IEM 1754 Dihydrobromide 50mg A14010-50
IEM 1754 Dihydrobromide 100mg A14010-100
IEM 1754 Dihydrobromide 10mM * 1mL in DMSO A14010-10mM-D

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

IEM 1754 Dihydrobromide is a voltage-dependent open-channel blocker of AMPA receptors.

IEM 1754 Dihydrobromide

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Chemical Information

Catalog Num A14010
Actions Blocker
M. Wt 412.25
Formula C16H30N2.2HBr
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 162831-31-4
Synonyms IEM1754
SMILES code C1[[email protected]@H]2C[[email protected]@H]3C[[email protected]]1C[[email protected]](C2)(C3)CNCCCCCN.Br.Br
Chemical Name 1,5-Pentanediamine, N1-(tricyclo[,7]dec-1-ylmethyl)-, hydrobromide (1:2)

Biological Activity

IEM 1754 Dihydrobromide is a voltage-dependent open-channel blocker of AMPA receptors.
GluR1 GluR3
6 μM6 μM


Solubility (25°C)* In vitro DMSO 82 mg/mL (198.9 mM)
Water 82 mg/mL (198.9 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.26 mL 121.29 mL 242.57mL
0.5 mM 4.85 mL 24.26 mL 48.51 mL
1 mM 2.43 mL 12.13 mL 24.26 mL
5 mM 0.49 mL 2.43 mL 4.85 mL

*The above data is based on the productmolecular weight 412.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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