IGF-1R inhibitor-4

Catalog No.: A34721
IGF-1R Inhibitor
IGF-1R inhibitor-4 is a potent inhibitor of insulin-like growth factor 1 receptor (IGF-1R), demonstrating an inhibition rate of 63% at a concentration of 10 μM. This compound is valuable in cancer research, as it interferes with IGF-1 signaling pathways that contribute to tumor cell proliferation and survival. Researchers can utilize IGF-1R inhibitor-4 to explore therapeutic strategies targeting IGF-1R in various malignancies.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionIGF-1R inhibitor-4 is a potent inhibitor of insulin-like growth factor 1 receptor (IGF-1R), demonstrating an inhibition rate of 63% at a concentration of 10 μM. This compound is valuable in cancer research, as it interferes with IGF-1 signaling pathways that contribute to tumor cell proliferation and survival. Researchers can utilize IGF-1R inhibitor-4 to explore therapeutic strategies targeting IGF-1R in various malignancies.
Product Information
Catalog NumA34721
FormulaC13H15ClN4O
Molecular Weight278.74
CAS Number443097-57-2
SMILESO=C1NC(NC2=CC=C(C=C2)Cl)=NN=C1C(C)(C)C
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