Ilexsaponin B2

Catalog No.: A42055
PDE5/PDEI Inhibitor
Ilexsaponin B2 is a saponin derived from the root of Ilex pubescens Hook. et Arn. It acts as a potent inhibitor of phosphodiesterase 5 (PDE5) and phosphodiesterase I (PDEI), with IC50 values of 48.8 μM and 477.5 μM, respectively. This compound is valuable for research applications focused on vascular biology and therapeutic areas related to erectile dysfunction and cardiovascular diseases.
Grouped product items
Size Price Stock Qty
1mg
$90.00
In stock
5mg
$220.00
In stock
10mg
$330.00
In stock
25mg
$550.00
In stock
50mg
$765.00
In stock
100mg
$1,015.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionIlexsaponin B2 is a saponin derived from the root of Ilex pubescens Hook. et Arn. It acts as a potent inhibitor of phosphodiesterase 5 (PDE5) and phosphodiesterase I (PDEI), with IC50 values of 48.8 μM and 477.5 μM, respectively. This compound is valuable for research applications focused on vascular biology and therapeutic areas related to erectile dysfunction and cardiovascular diseases.
Product Information
Catalog NumA42055
FormulaC47H76O17
Molecular Weight913.10
CAS Number108906-69-0
SMILESOC([C@]12[C@]([C@](O)([C@@H](C)CC2)C)([H])C3=CC[C@@]([C@@]4([C@@](C(C)([C@@H](O[C@@]5([H])[C@@H]([C@H]([C@H](O)CO5)O)O[C@@]6([H])[C@@H]([C@H]([C@H](O)[C@@H](CO)O6)O)O[C@@]7([H])[C@@H]([C@@H]([C@@H](O)[C@H](C)O7)O)O)CC4)C)([H])CC8)C)([H])[C@]8(C)[C@]3(C)CC1)=O
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