Iloperidone carboxylic acid

Catalog No.: A46038
5-HT2A Receptor Ligand
Iloperidone carboxylic acid is a ligand targeting the 5-HT2A receptor. This metabolite of Iloperidone demonstrates a strong affinity for the 5-HT2A receptor, with a pKi value of 8.15, while also showing moderate binding affinity to adrenergic receptors α1, α2B, and α2C. It serves as a valuable reagent for research exploring neuropharmacology and the modulation of serotonergic signaling in various biological contexts.
Grouped product items
Size Price Stock Qty
500µg
$60.00
In stock
1mg
$120.00
In stock
5mg
$410.00
In stock
10mg
$675.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
DescriptionIloperidone carboxylic acid is a ligand targeting the 5-HT2A receptor. This metabolite of Iloperidone demonstrates a strong affinity for the 5-HT2A receptor, with a pKi value of 8.15, while also showing moderate binding affinity to adrenergic receptors α1, α2B, and α2C. It serves as a valuable reagent for research exploring neuropharmacology and the modulation of serotonergic signaling in various biological contexts.
Product Information
Catalog NumA46038
FormulaC23H25FN2O5
Molecular Weight428.45
CAS Number475110-48-6
SMILESCOC1=C(OCCCN2CCC(C3=NOC4=C3C=CC(F)=C4)CC2)C=CC(C(O)=O)=C1
SynonymsP95-12113
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