Importazole

Catalog No.: A17128

nuclear transport receptor importin-β inhibitor

Importazole

Importazole Chemical Structure

CAS NO. 662163-81-7

Importazole is a cell-permeable inhibitor of importin-β. It specifically inhibits the function of importin-β, likely by altering its interaction with RanGTP.

Availability: In stock

Package Price Qty
5 mg
$40.00
10 mg
$70.00
50 mg
$280.00
100 mg
$480.00
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Biological Activity

Importazole is a cell-permeable inhibitor of importin-β. It specifically inhibits the function of importin-β, likely by altering its interaction with RanGTP.
In vitro DMSO 58 mg/mL (182.15 mM)
Water Insoluble
Ethanol 29 mg/mL (91.07 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.41 mL 157.04 mL 314.07 mL
0.5 mM 6.28 mL 31.41 mL 62.81 mL
1 mM 3.14 mL 15.7 mL 31.41 mL
5 mM 0.63 mL 3.14 mL 6.28 mL

*The above data is based on the productmolecular weight 318.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17128
Actions Inhibitor
CAS No. 662163-81-7
Formula C20H22N4
M. Wt 318.4
Purity >98%
Synonyms IPZ
SMILES [H]N(C(C1=CC=CC=C1)C)C2=NC(N3CCCC3)=NC4=C2C=CC=C4
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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