INCB024360 analog

Catalog No.: A13004

IDO1 inhibitor

INCB024360 analog

INCB024360 analog Chemical Structure

CAS NO. 914471-09-3

INCB024360 is an orally available hydroxyamidine and inhibitor of indoleamine 2,3-dioxygenase (IDO1), with potential immunomodulating and antineoplastic activities.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $55.00

Special Price $49.50

10 mg

Regular Price: $80.00

Special Price $72.00

25 mg

Regular Price: $150.00

Special Price $135.00

50 mg

Regular Price: $240.00

Special Price $216.00

10mM * 1mL in DMSO

Regular Price: $102.00

Special Price $91.80

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

INCB024360 is an orally available hydroxyamidine and inhibitor of indoleamine 2,3-dioxygenase (IDO1), with potential immunomodulating and antineoplastic activities.
Targets
IDO1
67 nM
In vitro DMSO 54 mg/mL (198.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol 54 mg/mL heating (198.79 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36.81 mL 184.07 mL 368.15 mL
0.5 mM 7.36 mL 36.81 mL 73.63 mL
1 mM 3.68 mL 18.41 mL 36.81 mL
5 mM 0.74 mL 3.68 mL 7.36 mL

*The above data is based on the productmolecular weight 271.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A13004
Actions Inhibitor
M. Wt 271.63
Formula C9H7ClFN5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 914471-09-3
Synonyms INCB-024360, INCB 024360
SMILES C1=CC(=C(C=C1N/C(=C\2/C(=NON2)N)/N=O)Cl)F

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