INK 128 (MLN0128)

Catalog No.: A11461

mTOR inhibitor

INK 128 (MLN0128)

INK 128 (MLN0128) Chemical Structure

CAS NO. 1224844-38-5

INK 128 is a TORC1/2 inhibitor, is also an orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity.

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$100.00
25 mg
$180.00
50 mg
$250.00
10mM * 1mL in DMSO
$80.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

INK 128 is a TORC1/2 inhibitor, is also an orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity.
Targets
Target Value
mTORki: 1.4nM
mTORki: 1.4nM
PI3KαIC50: 219nM
PI3KγIC50: 221nM
PI3KδIC50: 230nM
PI3KβIC50: 5293nM
In vitro (25°C) DMSO 58 mg/mL (187.5 mM)
Water Insoluble
Ethanol 2 mg/mL (6.46 mM)
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.33 mL 161.66 mL 323.31 mL
0.5 mM 6.47 mL 32.33 mL 64.66 mL
1 mM 3.23 mL 16.17 mL 32.33 mL
5 mM 0.65 mL 3.23 mL 6.47 mL

*The above data is based on the productmolecular weight 309.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11461
Actions Inhibitor
CAS No. 1224844-38-5
Formula C15H15N7O
M. Wt 309.3
Purity >98%
Synonyms INK128, INK-128
SMILES CC(C)N1C2=C(C(=N1)C3=CC4=C(C=C3)OC(=N4)N)C(=NC=N2)N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy INK 128 (MLN0128) | INK 128 (MLN0128) Supplier | purchase | cost | manufacturer | order | distributor | buy 1224844-38-5| 1224844-38-5 Supplier | purchase 1224844-38-5 | 1224844-38-5 cost | 1224844-38-5 manufacturer | order 1224844-38-5 | 1224844-38-5 distributor
Rewards