Inolitazone hydrochloride hydrate

Catalog No.: A40043
PPAR Agonist
Inolitazone hydrochloride hydrate is a high-affinity agonist of the peroxisome proliferator-activated receptor gamma (PPARγ), exhibiting an EC50 value significantly lower than that of Rosiglitazone. It selectively activates PPARγ without inhibiting RIE cells lacking this receptor. This compound is primarily utilized in cancer research, providing insights into the mechanisms of PPARγ in tumor biology and potential therapeutic applications.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionInolitazone hydrochloride hydrate is a high-affinity agonist of the peroxisome proliferator-activated receptor gamma (PPARγ), exhibiting an EC50 value significantly lower than that of Rosiglitazone. It selectively activates PPARγ without inhibiting RIE cells lacking this receptor. This compound is primarily utilized in cancer research, providing insights into the mechanisms of PPARγ in tumor biology and potential therapeutic applications.
Product Information
Catalog NumA40043
FormulaC27H30Cl2N4O5S
Molecular Weight593.52
CAS Number1048002-36-3
SMILESCC1=C(N)C(C)=CC(OC2=CC(N(C)C(COC3=CC=C(CC4C(NC(S4)=O)=O)C=C3)=N5)=C5C=C2)=C1.O.Cl.Cl
SynonymsEfatutazone hydrochloride hydrate; CS-7017 hydrochloride hydrate; RS5444 hydrochloride hydrate
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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