Integrin-IN-2 is a pan αv integrin inhibitor that demonstrates oral bioavailability. It effectively enhances the binding affinities for αvβ6, αvβ3, αvβ5, and αvβ8, with pIC50 values of 7.8, 8.4, 8.4, and 7.4, respectively. This compound is valuable for research applications focused on cancer metastasis and fibrosis, providing a tool for investigating integrin-mediated cellular processes.
Integrin-IN-2 is a pan αv integrin inhibitor that demonstrates oral bioavailability. It effectively enhances the binding affinities for αvβ6, αvβ3, αvβ5, and αvβ8, with pIC50 values of 7.8, 8.4, 8.4, and 7.4, respectively. This compound is valuable for research applications focused on cancer metastasis and fibrosis, providing a tool for investigating integrin-mediated cellular processes.
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