INU-152

Catalog No.: A32704
B-Raf Inhibitor
INU-152 is a potent and selective inhibitor of B-Raf, a key kinase in the MAPK signaling pathway. This compound effectively reduces tumor cell proliferation, enhances autophagy, and induces apoptosis through the inhibition of B-Raf activity. INU-152 demonstrates significant cytotoxicity against cancer cells transformed with v-Ha-ras (Ras-NIH 3T3), making it a valuable tool for cancer research applications.
Grouped product items
Size Price Stock Qty
25mg
$1,530.00
In stock
50mg
$1,950.00
In stock
100mg
$2,480.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionINU-152 is a potent and selective inhibitor of B-Raf, a key kinase in the MAPK signaling pathway. This compound effectively reduces tumor cell proliferation, enhances autophagy, and induces apoptosis through the inhibition of B-Raf activity. INU-152 demonstrates significant cytotoxicity against cancer cells transformed with v-Ha-ras (Ras-NIH 3T3), making it a valuable tool for cancer research applications.
Product Information
Catalog NumA32704
FormulaC20H13F2N7O3S
Molecular Weight469.42
CAS Number1380228-30-7
SMILESFC(C=CC(NS(=O)(C1=COC=C1)=O)=C2F)=C2NC3=NC=CC=C3C4=NC=NC5=C4N=CN5
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