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Inupadenant hydrochloride

Catalog No.: A57932
A2A Receptor Antagonist
Inupadenant hydrochloride is a selective antagonist of the A2A receptor, known for its oral bioactivity. This compound is unable to cross the blood-brain barrier, making it suitable for peripherally-targeted research applications. Inupadenant hydrochloride has been shown to enhance humoral immune responses and demonstrates anti-tumor activity, providing potential for investigations in immunotherapy and cancer treatment.
Inupadenant hydrochloride 2411004-22-1 A2A Receptor Antagonist
Grouped product items
Size Price Stock Qty
5mg
$655.00
In stock
10mg
$1,075.00
In stock
25mg
$2,150.00
In stock
50mg
$3,360.00
In stock
100mg
$5,120.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionInupadenant hydrochloride is a selective antagonist of the A2A receptor, known for its oral bioactivity. This compound is unable to cross the blood-brain barrier, making it suitable for peripherally-targeted research applications. Inupadenant hydrochloride has been shown to enhance humoral immune responses and demonstrates anti-tumor activity, providing potential for investigations in immunotherapy and cancer treatment.
Product Information
Catalog NumA57932
FormulaC25H27ClF2N8O4S2
Molecular Weight641.11
CAS Number2411004-22-1
SMILESO=C1SC(C2=NC(C3=CC=CO3)=NN2C(N)=N4)=C4N1CCN5CCN(C(C(F)=C6)=CC(OCC[S@](C)=O)=C6F)CC5.[H]Cl
SynonymsEOS-850 hydrochloride
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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GPCR/G Protein > Adenosine Receptors