Signaling Pathway
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| Discription | Irinotecan (CPT 11), a compound within the camptothecin family, is an inhibitor of topoisomerase 1 involved in cellular DNA replication and transcription. | ||
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| Catalog Num | A10479 |
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| Formula | C33H38N4O6.HCl.3H2O |
| Molecular Weight | 677.2 |
| CAS Number | 136572-09-3 |
| SMILES | CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7.O.O.O.Cl |
| Synonyms | CPT 11, Camptosar, Campto, Irinotecan |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 92 mg/mL (135.86 mM) | |
| Water | 1 mg/mL (1.47 mM) | ||
| Ethanol | 6 mg/mL (8.85 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.77 mL | 73.83 mL | 147.67 mL |
| 0.5 mM | 2.95 mL | 14.77 mL | 29.53 mL |
| 1 mM | 1.48 mL | 7.38 mL | 14.77 mL |
| 5 mM | 0.3 mL | 1.48 mL | 2.95 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
