Irinotecan HCl Trihydrate (Campto)

Catalog No.: A10479

Topoisomerase inhibitor

Irinotecan HCl Trihydrate (Campto) Chemical Structure

CAS NO. 136572-09-3

Irinotecan (CPT 11), a compound within the camptothecin family, is an inhibitor of topoisomerase 1 involved in cellular DNA replication and transcription.

Availability: In stock

Package Price Qty
200 mg
$50.00
10mM * 1mL in DMSO
$61.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Irinotecan (CPT 11), a compound within the camptothecin family, is an inhibitor of topoisomerase 1 involved in cellular DNA replication and transcription.
Targets
Topo I
In vitro (25°C) DMSO 100 mg/mL (147.67 mM)
Water 1 mg/mL (1.47 mM)
Ethanol 7 mg/mL (10.33 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.77 mL 73.83 mL 147.67 mL
0.5 mM 2.95 mL 14.77 mL 29.53 mL
1 mM 1.48 mL 7.38 mL 14.77 mL
5 mM 0.3 mL 1.48 mL 2.95 mL

*The above data is based on the productmolecular weight 677.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10479
Actions Inhibitor
M. Wt 677.2
Formula C33H38N4O6.HCl.3H2O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 136572-09-3
Synonyms CPT 11, Camptosar, Campto, Irinotecan
SMILES CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[[email protected]@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7.O.O.O.Cl

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