ISIS 5132

Catalog No.: A40718
Raf Inhibitor
ISIS 5132 is a phosphorothioate oligonucleotide consisting of 20 bases that specifically targets and down-regulates c-raf expression. By inhibiting the expression of c-raf, this compound modulates downstream signaling pathways involved in cell proliferation and survival. ISIS 5132 is valuable for research applications focused on cancer biology and therapeutic development associated with Raf signaling pathways.
Grouped product items
Size Stock
5mg
10mg
50mg
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionISIS 5132 is a phosphorothioate oligonucleotide consisting of 20 bases that specifically targets and down-regulates c-raf expression. By inhibiting the expression of c-raf, this compound modulates downstream signaling pathways involved in cell proliferation and survival. ISIS 5132 is valuable for research applications focused on cancer biology and therapeutic development associated with Raf signaling pathways.
Product Information
Catalog NumA40718
CAS Number177075-18-2
SMILES[ISIS 5132]
SynonymsCGP 69846A; ISIS 9271
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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